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This Applet is accompanies the review paper by Shouval, Wang and Wittenberg (2010) in the special issue on STDP of the Frountiers Journal. The applet implements the CaDP model as in Shouval et. al (2002). A simple mechanistic model which assumes that the underlying biophysics cannot be ignored. This model demonstrates the ability to qualitatively produce the fequency dependence and dependence on the number of postsynaptic spikes as in the experimental data. Different parameters can either be chosen explicitly in the applet boxes, or by choosing the preset parameter sets underlined in the text box on the upper left corner of the applet.