Membrane Potential Laboratory


The interactive model presented below simultaneously plots membrane potentials as predicted by the The Nernst relationship for K+ is $$E_k=60\textrm{log}\frac{[K^+]_o}{[K^+]_i} (mV)$$ and is depicted by the "blue" curve where The GHK relationship is $$V_m=60\textrm{log}\frac{[K^+]_o + \alpha[Na^+]_o}{[K^+]_i + \alpha[Na^+]_i} (mV)$$ It is depicted by the "orange" curve where

Experiment with altering [K+]i and/or alpha to see how changes in these values alter the membrane potential for any given value of [K+]o .